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CSV View April 18, 2022 through April 18, 2024 All Errata for FCC How to use
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Monograph Title Section Sort ascending Source Publication Page Number Errata Effective Date Target Errata Print Publication Target Online Fix Publication Description
APPENDIX XV: MICROBIAL FOOD CULTURES INCLUDING PROBIOTICS USES OF MICROBIAL FOOD CULTURES IN FOOD PRODUCTION/MFC Used as Probiotics Second Supplement to FCC 11th Edition Online 1-Jul-2019 FCC 12th Edition Third Supplement to FCC 11th Edition In footnote 12: Change http://www.cast-science.org/publications/index.cfm/probiotics_their_pot….
to:
Read More
APPENDIX XV: MICROBIAL FOOD CULTURES INCLUDING PROBIOTICS USES OF MICROBIAL FOOD CULTURES IN FOOD PRODUCTION FCC 11th Edition 1453 1-Jan-2019 FCC 12th Edition Second Supplement to FCC 11th Edition In MFC Used to Transform Foods/footnote 4: Change
10.1002/mnfr.201100010, http://www.dfg.de/download/pdf/dfg_im_profil/reden_stellungnahmen/2-1… Read More
APPENDIX X: CARBOHYDRATES (STARCHES, SUGARS, AND RELATED SUBSTANCES) SULFUR DIOXIDE DETERMINATION FCC 10th Edition 1537 1-Jan-2018 FCC 11th Edition FCC 11th Edition Line 2: Change
(Based on AOAC Method 962.16)
to:
(Based on AOAC Method 990.28)
TBHQ SPECIFIC TESTS/Ultraviolet Absorbance (Polynuclear Hydrocarbons) FCC 9th Edition 1192 1-Jul-2014 First Supplement to FCC 9th Edition First Supplement to FCC 9th Edition Line 18 of Sample preparation: Change
0.5% solution of 75 : 25 ethanol and water–ascorbic acid.
to:
25:75 (v/v) ethanol water solution containing 0.5% ascorbic acid.
INVERT SUGAR SPECIFIC TESTS/Total Solids FCC 8th Edition 567 1-Jul-2013 FCC 9th Edition Third Supplement to FCC 8th Edition Line 1: Change
Total Solids, Invert Sugar, Appendix X
to:
Total Solids, Appendix X
AND
Line 1 of Analysis: Change
Determine as directed using the table provided.
to:
Determine as directed under Invert Sugar.
GLUCOSE SYRUP, DRIED SPECIFIC TESTS/Total Solids FCC 9th Edition 528 1-Jul-2015 FCC 10th Edition Third Supplement to FCC 9th Edition Line 1 of Acceptance criteria: Change
NLT 90% when the reducing sugar content is 88% or greater; NLT 93% when the reducing sugar content is between 20.0% and 88.0%
to:
NLT 90% when the reducing sugar content is 88% or greater, calculated on the anhydrous basis; NLT 93% when the… Read More
YEAST EXTRACT SPECIFIC TESTS/Sodium Chloride FCC 8th Edition 1203 1-Jan-2014 FCC 9th Edition FCC 9th Edition Line 1 of Analysis: Change
suitable spectrophotometer,
to:
suitable atomic absorption spectrophotometer,
POTASSIUM PHOSPHATE, DIBASIC SPECIFIC TESTS/Pyrophosphate FCC 11th Edition 981 1-Jul-2019 FCC 12th Edition Third Supplement to FCC 11th Edition In Standard stock solution: Change
The resulting solution contains 1000 mg/mL of pyrophosphate anion
to:
The resulting solution contains 1000 µg/mL of pyrophosphate anion
SODIUM PHOSPHATE, DIBASIC SPECIFIC TESTS/Pyrophosphate FCC 8th Edition 1052 1-Jan-2014 FCC 9th Edition FCC 9th Edition Line 2 of Standard stock solution: Change
tetra sodium pyrophosphate
to:
tetrasodium pyrophosphate
AND
Line 19 of Analysis: Change
tetra sodium pyrophosphate
to:
tetrasodium pyrophosphate
YEAST EXTRACT SPECIFIC TESTS/Potassium FCC 8th Edition 1203 1-Jan-2014 FCC 9th Edition FCC 9th Edition Line 1 of Analysis: Change
suitable spectrophotometer,
to:
suitable atomic absorption spectrophotometer,
CITRIC ACID SPECIFIC TESTS/Oxalate FCC Online Online 1-Jan-2023 NA Second Supplement to FCC 13th Edition In Analysis: Change
Transfer the solution into a glass cylinder with a ground glass stopper and add an equal volume of concentrated hydrochloric acid and 0.25 mL of 5% potassium ferricyanate solution.
to:
Transfer the solution into a glass cylinder… Read More
MALIC ACID SPECIFIC TESTS/Optical (Specific) Rotation, Appendix IIB FCC 9th Edition 728 1-Jan-2015 FCC 10th Edition Second Supplement to FCC 9th Edition Line 1 of Acceptance criteria: Change
[α]D25 between −0.10° and +0.10°
to:
[α]D25 between −0.10° and +0.10°, on the as-is basis
L-SERINE SPECIFIC TESTS/Optical (Specific) Rotation, Appendix IIB FCC 9th Edition 1061 1-Jan-2015 FCC 10th Edition Second Supplement to FCC 9th Edition Line 3 of Acceptance criteria: Change
+13°
to:
+13.2°
CASEIN AND CASEINATE SALTS SPECIFIC TESTS/Lactose FCC 9th Edition 263 1-Jul-2014 First Supplement to FCC 9th Edition First Supplement to FCC 9th Edition Line 2 of Standard stock solutions: Change
500-mL
to:
100-mL
SODIUM CHLORIDE SPECIFIC TESTS/Iron FCC 8th Edition 1023 1-Jan-2013 FCC 9th Edition Second Supplement to FCC 8th Edition Line 3 of Sample solution: Delete
Add 40 mg of ammonium persulfate crystals and 10 mL of ammonium thiocyanate TS.
SODIUM CHLORIDE SPECIFIC TESTS/Iron FCC 9th Edition 1078 1-Jan-2015 FCC 10th Edition Second Supplement to FCC 9th Edition Line 1 of Control solution: Change
Dissolve 10 mL of Iron Standard Solution
to:
Dissolve 1 mL of Iron Standard Solution
SODIUM HYALURONATE (FROM MICROBIAL FERMENTATION) SPECIFIC TESTS/Intrinsic Viscosity FCC 10th Edition 1169 1-Jan-2018 FCC 11th Edition FCC 11th Edition First equation in Analysis: Change
ηr = [ti (B/ti2)]/[t0 – (B/ti2)]
to:
ηr = [ti – (B/ti2)]/[t0 − (B/t02)]
PALM OIL (UNHYDROGENATED) SPECIFIC TESTS/Free Fatty Acids FCC 10th Edition 952 1-Jul-2016 FCC 11th Edition FCC 10th Edition Line 4 of Analysis: Change
Free fatty acids as lauric acid, e = 25.6
to:
Free fatty acids as palmitic acid, e = 25.6
KRILL OIL SPECIFIC TESTS/Content of Astaxanthin FCC 9th Edition 654 1-Jul-2014 First Supplement to FCC 9th Edition First Supplement to FCC 9th Edition Line 4 of Analysis: Change
percent
to:
amount
DIOCTYL SODIUM SULFOSUCCINATE SPECIFIC TESTS/Chromatographic Purity/Table 1 FCC 8th Edition 363 1-Jul-2013 FCC 9th Edition Third Supplement to FCC 8th Edition Row 1 of Column 2: Change
Relative Retention Time (min)
to:
Approximate Retention Time (min)
DIOCTYL SODIUM SULFOSUCCINATE SPECIFIC TESTS/Chromatographic Purity FCC 8th Edition 363 1-Jan-2013 FCC 9th Edition Second Supplement to FCC 8th Edition Line 13 of Analysis: Change
rs is the dioctyl sodium sulfosuccinate response obtained from the Standard solution.
to:
rs is the docusate sodium related compound B response obtained from the Standard solution.
VITAMIN A SPECIFIC TESTS/Absorbance Ratio FCC 11th Edition 1239 1-Jan-2020 FCC 12th Edition FCC 12th Edition Change
[Note—The Absorbance ratio is the ratio of absorbances corrected/observed at 325 nm.]
to:
[Note—The Absorbance ratio is the ratio of absorbances corrected/observed at 325 nm. Only apply to other forms of Vitamin A in the Assay… Read More
Color Determination SODIUM SULFATE FCC 9th Edition 1366 1-Jul-2014 First Supplement to FCC 9th Edition First Supplement to FCC 9th Edition Line 8: Change
tetrahydroquinone sulfate indicator
to
tetrahydroxyquinone indicator(CAS: 319-89-1)5
AND
Add a footnote
[fn: 5 >95% purity (Catalog Number 099165, Matrix Scientific, Columbia, SC, USA), or equivalent].
APPENDIX XV: MICROBIAL FOOD CULTURES INCLUDING PROBIOTICS SAFETY/Qualified Presumption of Safety by the European Food Safety Authority Second Supplement to FCC 11th Edition Online 1-Jul-2019 FCC 12th Edition Third Supplement to FCC 11th Edition In footnote 27: Change
http://www.efsa.europa.eu/en/topics/topic/qps.htm.
to:
http://www.efsa.europa.eu.
Pepsin Activity REAGENTS AND SOLUTIONS Second Supplement to FCC 8th Edition 1789 27-Dec-2013 FCC 9th Edition FCC 9th Edition Line 3 of Standard Solutions: Change
0.45–0.90
to:
0.70– 1.25
Pepsin Activity REAGENTS AND SOLUTIONS Second Supplement to FCC 8th Edition 1789 1-Jan-2014 FCC 9th Edition FCC 9th Edition Line 3 of Sample Solution: Change
0.60–0.70
to:
0.9–1.0
APPENDIX V: ENZYME ASSAYS PLANT PROTEOLYTIC ACTIVITY FCC 11th Edition 1389 1-Jul-2019 FCC 12th Edition Third Supplement to FCC 11th Edition In Reagents and Solutions/Stock Standard Solution: Change
USP Papain Reference Standard
to:
USP Papain RS
AND
In the third paragraph of Calculation: Change
USP Papain Reference Standard,
to:
USP Papain RS,
IDENTIFICATION TESTS PHOSPHATE FCC 9th Edition 1343 1-Jul-2015 FCC 10th Edition Third Supplement to FCC 9th Edition Line 3: Change
With ammonium molybdate TS, a yellow precipitate, which is soluble in 6 N ammonium hydroxide, is formed.
to:
Acidified solutions of orthophosphates yield a yellow precipitate with ammonium molybdate TS, which is soluble in 6 N ammonium hydroxide.
APPENDIX XIII PESTICIDE RESIDUES: ADULTERANTS AND CONTAMINANTS IN FOOD INGREDIENTS Third Supplement to FCC 9th Edition Online 1-Jan-2016 FCC 10th Edition FCC 10th Edition Please see the compendial notice here: http://www.usp.org/food-ingredients/notices/correction-fcc-9-third-supp…
APPENDIX XVI: PROTEIN-BASED INGREDIENTS PEPTIDE MAPPING FOR IDENTIFICATION OF SPECIES IN PROTEIN INGREDIENTS Second Supplement to FCC 12th Edition 1934 1-Jul-2021 Third Supplement to FCC 12th Edition Third Supplement to FCC 12th Edition In Table 10: Change
Rice (glutelin)
to:
Pea (vicilin)
AND
In Table 10: Change
Pea (vicilin)
to:
Rice (glutelin)
BUTYL STEARATE OTHER REQUIREMENTS/Saponification Value, Appendix VII FCC 9th Edition 177 1-Jan-2015 FCC 10th Edition Second Supplement to FCC 9th Edition Line 1 of Acceptance criteria: Change
65–180
to:
165–180
GERANIOL OTHER REQUIREMENTS FCC 8th Edition 482 1-Jan-2013 FCC 9th Edition Second Supplement to FCC 8th Edition Line 1 of Aldehydes: Change
M-2d, Appendix XI
to:
M-2c, Appendix XI
ISOPULEGOL OTHER REQUIREMENTS FCC 8th Edition 608 1-Jan-2013 FCC 9th Edition Second Supplement to FCC 8th Edition Line 1: Change
Angular Rotation, Aldehydes, M-2d, Appendix XI
to:
Aldehydes, M-2c, Appendix XI
CITRONELLOL OTHER REQUIREMENTS FCC 8th Edition 266 1-Jul-2013 FCC 9th Edition Third Supplement to FCC 8th Edition Line 1 of Aldehydes: Change
M2-d, Appendix XI
to:
M2-c, Appendix XI
TEST SOLUTIONS (TS) AND OTHER REAGENTS NITRIC ACID FCC 9th Edition 1486 1-Jul-2015 FCC 10th Edition Third Supplement to FCC 9th Edition Line 2: Delete
(69.0%–71.0% of HNO3)
FLUORIDE LIMIT TEST METHOD II (ION-SELECTIVE ELECTRODE METHOD A) FCC 9th Edition 1350 1-Jan-2015 FCC 10th Edition Second Supplement to FCC 9th Edition Line 4 of Fluoride Standard: Change
1000 mg
to:
1000 µg
AND
Line 2 of Fluoride Standard Solution: Delete
to a 1000-mL volumetric flask, and dilute with water to volume. Take 1 mL of this solution and transfer
APPENDIX XV: MICROBIAL FOOD CULTURES INCLUDING PROBIOTICS INTRODUCTION TO MICROBIAL FOOD CULTURES FCC 11th Edition 1453 1-Jan-2019 FCC 12th Edition Second Supplement to FCC 11th Edition In footnote 2: Change
[cited 5 March 2011]. Available from ftp://ftp.fao.org/docrep/fao/009/a0512e/a0512e00.pdf.
to:
[cited 30 August 2018]. Available from… Read More
APPENDIX II: PHYSICAL TESTS AND DETERMINATIONS/C. OTHERS INSOLUBLE FOREIGN MATTER IN AMINO ACIDS/Apparatus FCC 10th Edition Online 1-Jul-2016 FCC 11th Edition FCC 10th Edition Footnote 4: Add
Millipore catalog number NY1H04700, or equivalent.
BRILLIANT BLACK PN IMPURITIES/Uncombined Intermediates and Products of Side Reactions FCC 9th Edition 150 1-Jul-2015 FCC 10th Edition Third Supplement to FCC 9th Edition Row 2 of Column 4 of Table 2: Change
134-34-9
to:
6409-21-8
LITHOL RUBINE BK IMPURITIES/Organic Impurities/Uncombined Intermediates and Products of Side Reactions and Subsidiary Coloring Matters FCC 11th Edition 707 1-Jan-2019 FCC 12th Edition Second Supplement to FCC 11th Edition In the Standard solution: Change
80 μL of Standard stock solution B,
to:
400 μL of Standard stock solution B,
SUCROSE IMPURITIES/Organic Impurities/Invert Sugar Second Supplement to FCC 9th Edition 1950 1-Jul-2015 FCC 10th Edition Third Supplement to FCC 9th Edition Line 1 of the second Equation of Analysis: Change
Result = (HS/HL) × (RRFS/WS) × [(WL × WISS2)/200] × 104
to:
Result = (HS/HL) × (RRFS/WS) × [(WL × W… Read More
SUCROSE IMPURITIES/Organic Impurities/Invert Sugar FCC 9th Edition 1165 1-Jan-2015 FCC 10th Edition Second Supplement to FCC 9th Edition Line 5 of Internal standard solution: Add
[NOTE—The change in the density of the solution due to addition of the lactose is insignificant, therefore 200 mL is equivalent to 200 g.]
AND
Line 26 of Analysis: Change
RRF = (HL/HS) × [(WSDF × W… Read More
MALIC ACID IMPURITIES/Organic Impurities FCC 8th Edition 683 1-Jan-2014 FCC 9th Edition FCC 9th Edition Line 2 of Fumaric and Maleic Acids: Delete
[Note—For all reference standards, do not dry before use and keep the containers tightly closed and protected from light. Determine the water content of the USP Fumaric Acid RS titrimetrically before use and make the necessary correction in… Read More
ASPARTAME IMPURITIES/Organic Impurities/5-Benzyl-3,6-dioxo-2-piperazineacetic Acid FCC 8th Edition 84 1-Jul-2013 FCC 9th Edition Third Supplement to FCC 8th Edition Line 10 of Analysis: Change
100%
to:
100
SODIUM FERROUS CITRATE IMPURITIES/Inorganic Impurities/Sulfate Second Supplement to FCC 9th Edition 1948 1-Jul-2015 FCC 10th Edition Third Supplement to FCC 9th Edition Line 3 of Acceptance criteria: Change
(NMT 4.8 mg/kg as SO4.)
to:
(NMT 4.8 g/kg as SO4.)
INOSITOL IMPURITIES/Inorganic Impurities/Sulfate, Choride and Sulfate Limit Tests, Chloride Limit Test, Appendix IIIB FCC 10th Edition 655 1-Jul-2017 Third Supplement to FCC 10th Edition Third Supplement to FCC 10th Edition Line 1: Change
Chloride Limit Test,
to:
Sulfate Limit Test,
FRUCTOSE IMPURITIES/Inorganic Impurities/Sulfate, Chloride and Sulfate Limit Tests, Chloride Limit Test, Appendix IIIB FCC 10th Edition 538 1-Jul-2017 Third Supplement to FCC 10th Edition Third Supplement to FCC 10th Edition Line 1: Change
Chloride Limit Test,
to:
Sulfate Limit Test,
SODIUM HYDROXIDE SOLUTIONS IMPURITIES/Inorganic Impurities/Mercury FCC 10th Edition 1171 1-Jan-2018 FCC 11th Edition FCC 11th Edition Line 1 of Sample solution: Change
Transfer 10.0 g of sample into a 100-mL beaker, dissolve in 15 mL of water, add 2 drops of phenolphthalein TS and, while constantly stirring, slowly neutralize with 1:2 hydrochloric acid. Add 1 mL of 1:5 sulfuric acid and 1 mL of a 40 mg/mL solution of… Read More
BENTONITE IMPURITIES/Inorganic Impurities/Lead FCC 10th Edition 132 1-May-2018 FCC 12th Edition First Supplement to FCC 11th Edition Line 3 of Acceptance criteria: Change
(NMT 4 mg/kg).
to:
(NMT 40 mg/kg).
CARMINE IMPURITIES/Inorganic Impurities/Lead FCC 8th Edition 215 1-Jan-2013 FCC 9th Edition Second Supplement to FCC 8th Edition Line 1 of Control: Change
10 µg Pb (10 mL of Diluted Standard Lead Solution)
to:
2 µg Pb (2 mL of Diluted Standard Lead Solution)